Matthias Mann
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Title |
Prof. Dr. rer. nat. Dr. Dr. h.c. |
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Position Title |
Director; Department of Proteomics and Signal Transduction |
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Birthdate |
10/10/1959 |
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Contact Details |
Max-Plnack-Institute of Biochemistry |
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Telefon |
+49 89 8578 2557 |
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Fax |
+49 89 8578 2219 |
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Website |
Education
• Georg August Universität Göttingen; B.A.; 1982; Physics, Mathematics
• Georg August Universität Göttingen; Master’s Degree; 1984; Physics
• Yale University; Ph.D.; 1988; Chemical Engineering
Professional Experience
1989–1992 Post doctoral fellow and later Senior Scientist in the Department of Molecular
Biology, University of Southern Denmark, Denmark
1992-1998 Group leader of the Protein & Peptide Group, European Molecular Biology
Laboratory (EMBL), Heidelberg
1998-2007 Professor of Bioinformatics, Department of Biochemistry and Molecular Biology,
University of Southern Denmark; Director of the Center for Experimental
BioInformatics (CEBI)
2005 - Director at the Max-Planck Institute of Biochemistry, Martinsried, Germany
2007 - Additional appointment as director of the Department of Proteomics, The Novo
Nordisk Foundation Center for Protein Research, Faculty of Heath Sciences,
University of Copenhagen, Denmark
Honors
• 1991 Malcom Award by the journal Organic Mass Spectrometry
• 1996 Mattauch Herzog Prize in Mass Spectrometry
• 1997 Hewlett-Packard Prize for Strategic Research in Automation of Sample Preparation
• 1998 Edman Prize by the “Methods in Protein Structure Analysis” Society
• 1999 Bieman Medal for Outstanding Achievement in Mass Spectrometry (American
Society for Mass Spectrometry)
• 1999 Named second most cited scientist in chemistry in the years 1994 to 1996 by the
Institute of Scientific Information
• 1999 Elected visiting professor Harvard Medical School 2/3
• 1999 Elected to the European Molecular Biology Organization (EMBO)
• 2001 Bernhard and Matha Rasmussen’s Memorial award in Cancer Research
• 2001 Meyenburg Cancer Research Award
• 2001 Fesenius Prize for Analytical Chemistry by the German Chemical Society
• 2004 Honorary Doctorate University Utrecht, Netherlands
• 2004 Lundbeck Nordic Research Prize
• 2004 Novo-Nordisk Prize (shared with Prof. Peter Roepstorff)
• 2005 Anfinsen Award of the Protein Society
• 2006 Biochemical Analysis Prize by the German Society for Clinical Chemistry and
Laboratory Medicine
• 2007 Honorary Professor at The Novo Nordisk Foundation Center for Protein Research,
Faculty of Health Sciences, University of Copenhagen
• 2007 2nd most cited European Scientist for the last ten years according to ScienceWatch
(ISI)
• 2008 HUPO Distinguished Achievement Award in Proteomic Sciences (Shared with Prof.
Denis Hochstrasser)
• 2010 Friedrich Wilhelm Joseph von Schelling Prize awarded by the Bavarian Academy of
Sciences
• 2011 Fyodor Lynen Lecture Medal 2011 (German Society of Biochemistry and Molecular
Biology)
• 2012 Leibniz Prize of the German Research Society
• 2012 Ernst Schering Prize
• 2012 Louis-Jeantet Foundation Prize for Medicine
• 2012 Körber European Science Award
• 2013 Elected member of Leopoldina German National Academy of Sciences
• 2013 Winner of m4 Award – Ministry of Economic Affairs supports Personalized Medicine
Recent Editorial Board Memberships
• Journal of Proteome Research
• Molecular and Cellular Proteomics
• Cell
• Carcinogenesis
Grants
Matthias Mann is currently involved in more than 13 external grants. Main sources: European
Union, BMBF (The German Federal Ministry of Education and Research), State of Bavaria
Ministry of Industry, Michael J Fox Foundation, Excellence Initiative of the Federal Republic of
Germany and the German Research Foundation (DFG) as well as joint projects with various
industrial concerns.
Publications
Dr. Mann has authored and co-authored more than 584 publications with more than 100,000
citations according to ISI (h-factor more than 150), making him one of the most highly cited
researchers worldwide
Ten most important publications to date (reverse order)
Azimifar SB, Nagaraj N, Cox J, Mann M. Cell-type-resolved quantitative proteomics of murine
liver. Cell Metab. 2014 Dec 2;20(6):1076-87
Scheltema RA, Hauschild JP, Lange O, Hornburg D, Denisov E, Damoc E, Kuehn A, Makarov A,
Mann M. The Q Exactive HF, a Benchtop Mass Spectrometer with a Pre-filter,
High-performance Quadrupole and an Ultra-high-field Orbitrap Analyzer. Mol Cell Proteomics.
2014 Dec;13(12):3698-708
Kulak NA, Pichler G, Paron I, Nagaraj N, Mann M. Minimal, encapsulated proteomic-sample
processing applied to copy-number estimation in eukaryotic cells. Nat Methods. 2014
Mar;11(3):319-24
Mann M, Kulak NA, Nagaraj N, Cox J. The coming age of complete, accurate, and ubiquitous
proteomes. Mol Cell. 2013 Feb 21;49(4):583-90
Meissner F, Scheltema RA, Mollenkopf HJ, Mann M. Direct proteomic quantification of the
secretome of activated immune cells. Science. 2013 Apr 26;340(6131):475-8
Cox J, Mann M. Quantitative, high-resolution proteomics for data-driven systems biology.
Annu Rev Biochem. 2011 Jun 7;80:273-99
Waanders LF, Chwalek K, Monetti M, Kumar C, Lammert E, Mann M. Quantitative proteomic
analysis of single pancreatic islets. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):18902-7
Cox J, Mann M. MaxQuant enables high peptide identification rates, individualized
p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol. 2008
Dec;26(12):1367-72
Adachi, J., C. Kumar, Y. Zhang, J. V. Olsen and M. Mann . "The human urinary proteome
contains more than 1500 proteins including a large proportion of membranes proteins." 2006
Genome Biol 7(9): R80
Aebersold, R. and M. Mann. "Mass spectrometry-based proteomics." Nature. 2003
422(6928): 198-207